This study reported that “radiofrequency radiation increased the frequency of micronuclei and lipid peroxidation and reduced glutathione contents, catalase and superoxide dismutase activities in the plasma of the exposed individuals. The induction of micronuclei may be due to the increase in free-radical production.
It demonstrated that staying near the mobile base stations and continuous use of mobile phones damage the DNA may have an adverse effect in the long run. The persistence of DNA unrepaired damage leads to genomic instability which may lead to several health disorders including the induction of cancer.”
Radiofrequency radiations (RFRs) emitted by mobile phone base stations have raised concerns on its adverse impact on humans residing in the vicinity of mobile phone base stations. Therefore, the present study was envisaged to evaluate the effect of RFR on the DNA damage and antioxidant status in cultured human peripheral blood lymphocytes (HPBLs) of individuals residing in the vicinity of mobile phone base stations and comparing it with healthy controls.
The study groups matched for various demographic data including age, gender, dietary pattern, smoking habit, alcohol consumption, duration of mobile phone use and average daily mobile phone use.
The RF power density of the exposed individuals was significantly higher (p < 0.0001) when compared to the control group. The HPBLs were cultured and the DNA damage was assessed by cytokinesis blocked micronucleus (MN) assay in the binucleate lymphocytes. The analyses of data from the exposed group (n = 40), residing within a perimeter of 80 meters of mobile base stations, showed significantly (p < 0.0001) higher frequency of micronuclei (MN) when compared to the control group, residing 300 meters away from the mobile base station/s.
The analysis of various antioxidants in the plasma of exposed individuals revealed a significant attrition in glutathione (GSH) concentration (p < 0.01), activities of catalase (CAT) (p < 0.001) and superoxide dismutase (SOD) (p < 0.001) and rise in lipid peroxidation (LOO) when compared to controls. Multiple linear regression analyses revealed a significant association among reduced GSH concentration (p < 0.05), CAT (p < 0.001) and SOD (p < 0.001) activities and elevated MN frequency (p < 0.001) and LOO (p < 0.001) with increasing RF power density.
Zothansiama, Zosangzuali M, Lalramdinpuii M, Jagetia GC.
Electromagn Biol Med. 2017 Aug 4:1-11. doi: 10.1080/15368378.2017.1350584.